Table 1. Testosterone formulations.
Composition (testosterone) |
Dose | Advantages | Disadvantages |
---|---|---|---|
Cypionate or Enanthate Intramuscular route |
200 mg every 2–3 weeks |
Low cost | Does not mimic testosterone circadian rhythm Plasmatic levels of testosterone reach high non-physiological levels (800–1,000 ng/dL) in the first days after administration |
Undecanoate testosterone oral route |
60–160 mg /day | Safe (no hepatotoxicity) |
2–4 daily doses |
Undecanoate testosterone intramuscular route |
800–1,000 mg every 12 weeks | Stable concentrations Physiologic doses |
High cost |
Gel (1%) (topic application) | 25–100 mg/day | Stable concentrations | High cost |
Skin-to-skin contact transference | |||
Not available in Brazil | |||
Patch (topic application) | 2.5–10 mg/day | Stable concentrations | High cost |
Skin irritation | |||
Not available in Brazil |