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. 2018 May;40(5):251–259. doi: 10.1055/s-0038-1666856

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This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 3 — Time course of the changes in metabolic flux due to oxidation of octanoate in perfused livers from fasted mice. 0.3 mM octanoate, [1-¹⁴C]octanoate (0.01 μCi/ml) plus 50 μM fatty acid-free bovine serum albumin were infused at 12–36 min of perfusion. Oxygen uptake and ¹⁴CO₂ production (panel A) and β-hydroxybutyrate and acetoacetate production (panel B) are reduced in the ovariectomized group (n = 4) compared with SHAM group (n = 4). Vertical bars represent mean standard errors. Asterisks indicate significant differences between the values as revealed by variance analysis with post hoc Newman-Keuls testing (p < 0.05).