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. Author manuscript; available in PMC: 2023 Jul 3.
Published in final edited form as: Sci Transl Med. 2022 May 11;14(644):eabj9954. doi: 10.1126/scitranslmed.abj9954

Fig. 2. Blood cell-type fraction trajectories in time, in subjects with persistent or resolved pain.

Fig. 2.

(A) Study design pictograms, showing contrasts in time in those with persistent pain (P; orange, column I), and in those with resolved pain (R; green, column II). (B to E) Box-and-whisker plots (columns I and II) showing the distributions of percent cell-type fraction at t0 and at t1. Cell-type fraction estimates inferred by CIBERSORT from transcriptomics data. P value obtained from logistic regression between the two time points shown on top; not significant (n.s.) when P > 0.05. Volcano plots (column III) for R patients, showing genes highly expressed in the corresponding row’s cell type (pink) versus all other genes (tan). (B) Neutrophils. (C) CD8+ T cells. (D) Natural killer (NK) cells, resting. (E) Mast cells, resting.