Table 3.
Hazard ratios for all-cause mortality following quintiles of alcohol use in 14 496 twins
| Quintiles | Cohort (between individuals) | Familial effect (est. between MZ twin pairs) | Individual-specific effects (est. within MZ twin pairs) | |||
|---|---|---|---|---|---|---|
| HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | |
| All levels of consume | ||||||
| 1 | 1.00 | – | 1.00 | – | 1.00 | |
| 2 | 0.88 | (0.80–0.97) | 0.87 | (0.75–1.00) | 0.95 | (0.78–1.16) |
| 3 | 0.93 | (0.84–1.03) | 0.97 | (0.85–1.12) | 0.91 | (0.74–1.11) |
| 4 | 0.87 | (0.79–0.95) | 0.85 | (0.75–0.97) | 1.00 | (0.81–1.25) |
| 5 | 0.89 | (0.59–0.67) | 0.85 | (0.71–1.01) | 1.08 | (0.83–1.41) |
| High consumers v. low | ||||||
| 1 + 2 + 3 | 1.00 | 1.00 | 1.00 | |||
| 4 + 5 | 0.92 | (0.86–0.99) | 0.88 | (0.79–0.98) | 1.09 | (0.96–1.25) |