Table 6.
Associations Between Brain-Age Delta and Cardiovascular Imaging Parameters
| Non-IHD |
IHD |
|||
|---|---|---|---|---|
| Beta Value | P Value | Beta Value | P Value | |
| LVEDVI, mL/m2 | −0.03 | <0.001 | −0.01 | 0.65 |
| LVEF, % | −0.03 | 0.05 | 0.01 | 1.00 |
| LVESVI, mL/m2 | −0.03 | 0.001 | −0.02 | 0.82 |
| LVMI, g/m2 | −0.03 | <0.001 | −0.004 | 1.00 |
| LVSVI, mL/m2 | −0.05 | <0.001 | −0.01 | 1.00 |
| RVEDVI, mL/m2 | −0.03 | <0.001 | −0.02 | 0.27 |
| RVESVI, mL/m2 | −0.03 | <0.001 | −0.03 | 0.95 |
| RVSVI, mL/m2 | −0.05 | <0.001 | −0.03 | 0.86 |
| LVGFI, % | −0.04 | <0.001 | 0.001 | 1.00 |
| M/V ratio, g/mL | 1.41 | 0.75 | 2.19 | 1.00 |
| Aortic distensibility, 10−3/mm Hg | −0.37 | <0.001 | −0.07 | 1.00 |
| TAC, mL/m2 × mm Hg | −1.65 | <0.001 | −1.29 | 0.66 |
The beta value is interpreted as the difference in the dependent variable (brain-age delta) for changing 1 U in the independent variable (exposure). Specifically, changing 1 U in the exposure leads to increasing (positive beta value) or decreasing (negative beta value) in brain-age delta. Bold indicates statistically significant after Bonferroni correction (P < 0.05).