Fig. 4.

Immune profiling of CD8⁺ T cells after treatment with ¹⁷⁷Lu-FAP-2287 and in combination with anti-PD-1 in MCA205-mFAP syngeneic tumor model. Individual percentage of T cells and CD8⁺ T cells with bars as mean ± SEM on day 8 and 13 pi (A), individual percentage of CD127⁺CD8⁺ cells and their CD127 MFI with bars as mean ± SEM on day 8 and 13 pi (B), and a summary table (C) are shown. Significant changes compared to vehicle in the summary table and between groups in the graph are denoted as * p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001