Table 4.

The results of meta-regression analysis of studies about differential diagnosis and prognosis prediction of OC

Covariates	Subgroup	No. of studies	Sensitivity [95%CI]	PSEN	Specificity [95%CI]	PSPE	P
Differential diagnosis
Number of patients	< 100	11	0.83 [0.75–0.92]	0.15	0.86 [0.80–0.91]	< 0.001	0.42
	≥ 100	5	0.84 [0.74–0.95]		0.78 [0.69–0.88]
Imaging modality	MRI	8	0.89 [0.82–0.95]	< 0.001	0.85 [0.78–0.93]	< 0.01	0.17
	CT	8	0.78 [0.68–0.88]		0.81 [0.73–0.89]
Type of ROI	2D	7	0.85 [0.76–0.95]	0.04	0.84 [0.75–0.92]	< 0.01	0.92
	3D	9	0.83 [0.74–0.92]		0.83 [0.76–0.90]
Type of features	Low-order	12	0.83 [0.75–0.91]	0.26	0.84 [0.78–0.90]	< 0.01	0.77
	High-order	4	0.86 [0.75–0.97]		0.81 [0.71–0.91]
Prognosis prediction
Number of patients	< 100	9	0.79 [0.73–0.85]	< 0.001	0.82 [0.76–0.87]	< 0.001	0.04
	≥ 100	4	0.73 [0.64–0.82]		0.73 [0.64–0.82]
Imaging modality	MRI	5	0.79 [0.71–0.88]	< 0.01	0.79 [0.70–0.87]	< 0.01	0.85
	CT	8	0.76 [0.69–0.84]		0.78 [0.71–0.85]
Type of ROI	2D	4	0.84 [0.77–0.92]	< 0.001	0.82 [0.74–0.91]	< 0.01	0.03
	3D	9	0.74 [0.68–0.80]		0.76 [0.69–0.83]
Type of features	Low-order	6	0.74 [0.65–0.82]	0.09	0.80 [0.70–0.85]	< 0.01	0.46
	High-order	7	0.81 [0.74–0.88]		0.77 [0.70–0.85]