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. 2023 Jul 3;9:45. doi: 10.1038/s41522-023-00414-3

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Schematic overview of quorum sensing pathways in Streptococcus (KEGG map02024 (https://www.genome.jp/pathway/map02024)). Genes are represented as orange boxes and the small yellow circles represent autoinducers. Two cells are depicted. b Phylogenetic tree of Streptococcus strains in COGR. The innermost circle is colored according to species and the second circle is colored by according to the oral sampling site. The outer three circles are colored according to the completeness of three quorum sensing pathways in Streptococcus. c The bar plot on the left shows the number of species harboring the complete quorum sensing pathway. The pie chart on the right shows the proportion of complete and incomplete coverage of the quorum sensing pathway in the indicated species of COGR. The color code in (c) is the same as that used in (b).