Table 1.
Baseline characteristics of the patients used for cell isolation.
| CAVD | no CAVD | |
|---|---|---|
| Total population | 5 | 5 |
| Clinical Parameters: | ||
| Male | 3 | 5 |
| Age (mean) | 65.5 ± 8.4 | 74 ± 5 |
| NYHA levels | 2.6 ± 0.5 | 2.5 ± 0.5 |
| CAD | 3 (50) | 5 (83.3) |
| Hypertension | 4 (66.7) | 6 (100) |
| AVA in cm2 | 0,74 ± 0.19 | 3.98 ± 1.3 |
| Vmax in m/s | 4.4 ± 0.31 | 1.9 ± 0.37 |
| pmean in mmHg | 47 ± 12.8 | N.D. |
| LV function (mean) | 55.7 ± 3.88 | 52.4 ± 14.6 |
| Mild-Severe Mitral regurgitation | 2 (30) | 3 (50) |
| Cardiovascular risk factors: | ||
| Type II DM | 2 (30) | 0 (0) |
| BMI (mean) | 25.4 ± 2.3 | 25.8 ± 3.2 |
| Dyslipidemia | 4 (66.7) | 5 (83.3) |
| Smoker | 1 (16.7) | 1 (16.7) |
| Creatinine in mg/dl (mean) | 0.86 ± 2.3 | 1.07 ± 0.55 |
Baseline demographic, and echocardiographic parameters of the validation study population. CAVD, calcified aortic valve disease; NYHA, New York heart association; CAD, coronary artery disease; Vmax, velocity maximum; Pmean, mean pressure; Type II DM, Type 2 diabetes mellitus; BMI, body mass index; LV, left ventricle; AVA, aortic valve area.