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. 2023 Jun 20;11:1208843. doi: 10.3389/fchem.2023.1208843

TABLE 3.

Half maximal inhibitory concentration of local anesthetics compared to reference standard in octanolic medium using the ABTS assay.

Medium Local anesthetics and References standards IC50 [mg/mL] log IC50 Hillslope
n-octanol Lidocaine 1.664 0.2212 2.168
Ropivacaine 1.908 0.2806 1.549
Bupivacaine 1.860 0.2695 1.722
Tocopherol (reference) 0.006713 −2.173 1.207

IC50 - half maximal inhibitory concentration.