TABLE 4.
ABTS assay of antioxidant activity of commercial formulations of local anesthetics in an aqueous medium.
| Local anesthetic | Concentration (mg/mL) | Absorbance values | ABTS˙+ scavenging effect (%) | ||
|---|---|---|---|---|---|
| After 30 min | After 2 h | After 30 min | After 2 h | ||
| Lidocaine hydrochloride | 20 | 0.0249 | 0.0172 | 90.13 | 93.04 |
| Bupivacaine hydrochloride | 5 | 0.1383 | 0.1048 | 45.16 | 57.62 |
| Ropivacaine hydrochloride | 7.5 | 0.1324 | 0.1048 | 47.50 | 57.62 |
| Lidocaine hydrochloride buffered to 7.4 pH | 10 | 0.00395 | N/P | 96.20 | N/P |
| Negative control | 0 | 0.2522 | 0.2473 | N/A | N/A |
ABTS˙+ scavenging effect was calculated using Eq. 1. N/A–not applicable. N/P–not performed.