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Hypothesis of the differentiation and proliferation abnormality of hepatic epithelial lineage cells in hepatocarcinogenesis and paradigm of the 2019 revision of the World Health Organization (WHO) classification of tumors. cHCC-CCA, combined hepatocellular-cholangiocarcinoma. CLC, cholangiolocarcinoma; HCC, hepatocellular carcinoma; iCCA, intrahepatic cholangiocarcinoma.
