Table 2.
Parameter comparison
| MRONJ | P-value | ||
|---|---|---|---|
|
| |||
| No (control group, n=210) | Yes (MRONJ group, n=130) | ||
| Age (yr) | 73.1±9.0 | 77.2±7.1 | <0.0011 |
| Medication administration | |||
| Oral | 82 (39.0) | 70 (53.8) | <0.0012 |
| Intravenous | 98 (46.7) | 29 (22.3) | |
| Both | 30 (14.3) | 31 (23.8) | |
| Duration of medication (yr) | 3.4±4.6 | 5.8±5.1 | <0.0011 |
| Medical history | |||
| Hypertension | 104 (49.5) | 85 (65.4) | 0.0042 |
| Hyperlipidemia | 47 (22.4) | 27 (20.8) | 0.726 |
| Anticoagulant | 29 (13.8) | 14 (10.8) | 0.412 |
| Diabetes mellitus | 41 (19.5) | 29 (22.3) | 0.552 |
| Heart disease | 23 (11.0) | 24 (18.5) | 0.051 |
| Thyroid disease | 10 (4.8) | 7 (5.4) | 0.798 |
| Liver disease | 4 (1.9) | 0 (0) | 0.113 |
| Kidney disease | 10 (4.8) | 4 (3.1) | 0.447 |
| Rheumatoid arthritis | 4 (1.9) | 7 (5.4) | 0.078 |
| Cancer | 10 (4.8) | 12 (9.2) | 0.104 |
| Dementia | 11 (5.2) | 2 (1.5) | 0.084 |
| Method of operation | |||
| Extraction | 180 (85.7) | 99 (76.2) | 0.0262 |
| Implantation | 30 (14.3) | 31 (23.8) | |
| No. of operated teeth | 2.3±1.6 | 1.7±1.0 | <0.0011 |
| Operation area | |||
| Maxilla | 93 (44.3) | 35 (26.9) | <0.0012 |
| Mandible | 87 (41.4) | 90 (69.2) | |
| Both | 30 (14.3) | 5 (3.8) | |
(MRONJ: medication-related osteonecrosis of the jaw)
Statistical analyses by 1Student’s t-test and 2chi-square test.
Values are presented as mean±standard deviations or number (%).