Table 3.
Radiotherapy treatment.
| Patients randomised | carboplatin + paclitaxel | cisplatin + capecitabine | ||
|---|---|---|---|---|
| 31 | 32 | |||
| n | % | n | % | |
| Planned dose | ||||
| 50Gy | 17 | 54.8 | 14 | 43.8 |
| 60Gy | 14 | 45.2 | 18 | 56.3 |
| Planned 50Gy∗ | ||||
| Given 50Gy in 25# | 15 | 88.2 | 12 | 85.7 |
| Other dose given | 2a | 11.8 | 1b | 7.1 |
| No RT given | 0 | 0.0 | 1 | 7.1∗∗ |
| Planned 60Gy∗ | ||||
| Given 60Gy in 25# | 10 | 71.4 | 16 | 88.9 |
| Other dose given | 4c | 28.6 | 2d | 11.1 |
| No RT given | 0 | 0.0 | 0 | 0.0 |
| Days from randomisation to start of RT – median (IQR) | 26 (25–32) | 26 (24–27) | ||
| Delays during RT | ||||
| Yes | 3 | 9.7 | 5 | 15.6 |
| No | 28 | 90.3 | 26 | 81.3 |
| N/A – no RT given | 0 | 0.0 | 1 | 3.1 |
| Median delay in days (IQR) | 8 (1–33) | 4 (1–7) | ||
| Reasons for delay | ||||
| Toxicity | 0 | 0.0 | 3 | 9.4 |
| Patient choice | 1 | 3.2 | 0 | 0.0 |
| Stent/replan/other treatment | 2 | 6.5 | 1 | 3.1 |
| Bank holiday | 0 | 0.0 | 1 | 3.1 |
Denominator for % is randomized patients except for ∗ where denominator is number of patients with this planned dose ∗∗withdrew from treatment after cycle 1 due to disease progression.
48Gy in 24# due to toxicity; 50Gy in 5# and 40gy in 20#.
36Gy in 18#.
50Gy in 25#; 51Gy in 27#; 50Gy in 25#; 60Gy in 5# and 48Gy in 20#.
24Gy in 12#; 60Gy in 1# and 57.6Gy in 3# and 42Gy in 21#.