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. 2023 Jun 26;61:102059. doi: 10.1016/j.eclinm.2023.102059

Table 3.

Radiotherapy treatment.

Patients randomised carboplatin + paclitaxel cisplatin + capecitabine
31 32
n % n %
Planned dose
 50Gy 17 54.8 14 43.8
 60Gy 14 45.2 18 56.3
Planned 50Gy∗
 Given 50Gy in 25# 15 88.2 12 85.7
 Other dose given 2a 11.8 1b 7.1
 No RT given 0 0.0 1 7.1∗∗
Planned 60Gy∗
 Given 60Gy in 25# 10 71.4 16 88.9
 Other dose given 4c 28.6 2d 11.1
 No RT given 0 0.0 0 0.0
Days from randomisation to start of RT – median (IQR) 26 (25–32) 26 (24–27)
Delays during RT
 Yes 3 9.7 5 15.6
 No 28 90.3 26 81.3
 N/A – no RT given 0 0.0 1 3.1
Median delay in days (IQR) 8 (1–33) 4 (1–7)
Reasons for delay
 Toxicity 0 0.0 3 9.4
 Patient choice 1 3.2 0 0.0
 Stent/replan/other treatment 2 6.5 1 3.1
 Bank holiday 0 0.0 1 3.1

Denominator for % is randomized patients except for ∗ where denominator is number of patients with this planned dose ∗∗withdrew from treatment after cycle 1 due to disease progression.

a

48Gy in 24# due to toxicity; 50Gy in 5# and 40gy in 20#.

b

36Gy in 18#.

c

50Gy in 25#; 51Gy in 27#; 50Gy in 25#; 60Gy in 5# and 48Gy in 20#.

d

24Gy in 12#; 60Gy in 1# and 57.6Gy in 3# and 42Gy in 21#.