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. 2023 Jul 3;6(7):e2321465. doi: 10.1001/jamanetworkopen.2023.21465

Table 1. Baseline Patient Characteristics Stratified by Risk Analysis Index.

Characteristic Patient groupa P value
Overall (N = 3058) RAI <40 (n = 2266) RAI ≥40 (n = 792)
Age, y
Median (IQR) 71 (63-79) 70 (62-78) 72 (64-82) NA
50-64 915 (29.9) 699 (30.8) 216 (27.3) <.001b
65-74 988 (32.3) 762 (33.6) 226 (28.5)
75-84 764 (25.0) 570 (25.2) 194 (24.5)
≥85 391 (12.8) 235 (10.4) 156 (19.7)
Sex
Women 1349 (44.1) 987 (43.6) 362 (45.7) .29
Men 1709 (55.9) 1279 (56.4) 430 (54.3)
Race
Black 377 (12.3) 217 (9.6) 160 (20.2) <.001
White 2117 (69.2) 1593 (70.3) 524 (66.2)
Otherc 95 (3.1) 67 (3.0) 28 (3.5)
Unknown 469 (15.3) 389 (17.2) 80 (10.1)
Location prior to admission
Home 2317 (75.8) 1777 (78.4) 540 (68.2) <.001
Other 741 (24.2) 489 (21.6) 252 (31.8)
Comorbidities and characteristics
Functional status
Independent 2725 (89.1) 2253 (99.4) 472 (59.6) <.001
Partially dependent 266 (8.7) 11 (0.5) 255 (32.2)
Totally dependent 67 (2.2) 2 (0.1) 65 (8.2)
Congestive heart failure 244 (8.0) 28 (1.2) 216 (27.3) <.001
Weight loss 130 (4.3) 11 (0.5) 119 (15.0) <.001
Diabetes 418 (13.7) 201 (8.9) 217 (27.4) <.001
Dyspnea 81 (2.6) 16 (0.7) 65 (8.2) <.001
Kidney failure 351 (11.5) 10 (0.4) 341 (43.1) <.001
Cancer 158 (5.2) 154 (6.8) 4 (0.5) <.001
Preoperative sepsis
None 2114 (69.1) 1685 (74.4) 429 (54.2) <.001
Sepsis 212 (6.9) 122 (5.4) 90 (11.4)
Septic shock 376 (12.3) 211 (9.3) 165 (20.8)
SIRS 356 (11.6) 248 (10.9) 108 (13.6)
ASA physical status
1 and 2 294 (9.6) 278 (12.3) 16 (2.0) <.001
3 1160 (37.9) 958 (42.3) 202 (25.5)
4 1139 (37.2) 672 (29.7) 467 (59.0)
5 465 (15.2) 358 (15.8) 107 (13.5)
Emergency surgery 1195 (39.1) 862 (38.0) 333 (42.0) .05
General anesthesia 2852 (93.3) 2112 (93.2) 740 (93.4) .82
Elective surgeryd 1248 (40.9) 1058 (46.8) 190 (24.0) <.001
Operative Stress Scoree
1-2 (low) 496 (17.1) 359 (16.8) 137 (17.9) <.001
3 (moderate) 1475 (50.8) 1026 (48.0) 449 (58.7)
4-5 (high) 930 (32.1) 751 (35.2) 179 (23.4)

Abbreviations: ASA, American Society of Anesthesiologists; NA, not applicable; RAI, Risk Analysis Index; SIRS, systemic inflammatory response syndrome.

a

Frailty was measured using the revised RAI (stratified as RAI <40 and RAI ≥40 [frailty]). Unless indicated otherwise, data are expressed as No. (%) of patients.

b

Corresponds to a χ2 test, as age was analyzed by category (the database censors ages for patients aged ≥90 years).

c

Includes American Indian or Alaska Native, Asian, and Native Hawaiian or other Pacific Islander.

d

Includes 3053 for elective surgery and nonelective surgery (5 [0.2%] missing).

e

Includes 2901 for Operative Stress Score low, moderate, and high (157 [5.1%] missing).