Panel.

Opportunities to address fertility during routine sickle cell disease care

• During new evaluations unless post-menopause

• At puberty onset or at delayed puberty diagnosis

• Initiation or change in SCD treatment approach including pursuit of curative therapy

• Initiation of hormonal contraception

• Screening for and treating priapism

• Transition from pediatric care; integration into adult care

• Annual preconception counseling and with family planning discussions

• Parents of children with SCD who can be offered referral to genetic counseling and discussion of comprehensive reproductive options (including, but not limited to IVF +PGT-M)