Figure 9.

sGAG content

(A–C) sGAG detected in (A) the scaffolds, (B) the conditioned medium, and (C) in total (conditioned medium + scaffold) after 25 days. Red color indicates sGAG found in the scaffolds and blue color indicates what was found in the conditioned medium. The different transparencies indicate different donors. All values are normalized to the DNA content of the respective scaffolds. UL: unloaded controls; MWB: multi-well bioreactor. For (A) and (B), error bars show SEM. ∗∗∗p < 0.001. Estimated marginal means are adjusted using the Tukey method.