Table 1.

Association between family history and breast cancer risk for Asian women

Type of family history	No. of studies	OR range	Pooled OR (95% CI)
Family history in any relatives	49	0.62–0.97	2.21 (1.91, 2.56)
By control type
Hospital-based control	24	0.62–4.35	2.15 (1.84, 2.51)
Population-based control	24	0.84–7.08	2.24 (1.73, 2.89)
By the woman’s age
Age < 50 years	2	1.81–3.33	1.87 (1.41, 2.48)
Age ≥ 50 years	2	1.13–2.04	1.97 (1.49, 2.60)
By menopausal status
Pre-menopausal	3	1.61–5.33	2.84 (1.50, 5.37)
Post-menopausal	3	0.92–4.61	2.09 (0.92, 4.78)
By region
East and Southeast Asia	23	0.62–7.08	2.05 (1.72, 2.43)
The rest of Asia	23	0.87–9.07	2.45 (1.90, 3.16)
Non-Asian countries	3	1.84–4.30	2.26 (1.42, 3.59)
Family history in first-degree relatives	33	0.50–9.52	2.46 (2.03, 2.97)
By menopausal status
Pre-menopausal	3	2.21–5.33	3.21 (1.84, 5.61)
Post-menopausal	3	2.43–4.61	2.78 (1.60, 4.82)
By the type of relatives
Mother	7	1.79–3.97	2.51 (1.88, 3.34)
Sister	7	1.23–5.80	2.03 (1.45, 2.83)
Family history in second-degree relatives	10	0.57–3.89	2.05 (1.56, 2.68)