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. 2023 Jul 4;20:53. doi: 10.1186/s12987-023-00448-x

Fig. 4.

Fig. 4

The CSF secretion rate and outflow resistance is not elevated in SHRs. a Representative time course traces of the fluorescence ratio of dextran (outflow/inflow) during ventriculo-cisternal perfusion of one WKY rat and one SHR. Squared insert indicates the region used for quantification of CSF secretion rates. b CSF secretion rate in WKY rats (n = 6) and SHRs (n = 6) quantified from the fluorescence ratio of dextran. c Representative ICP traces of one WKY rat and one SHR undergoing measurements of CSF outflow resistance by infusion of aCSF at rates indicated in the figure. e CSF outflow resistance in WKY rats (n = 6) and SHRs (n = 6). Error bars represent standard deviation and statistical significance was tested with an unpaired two-tailed t-test. NS = not significant