Table 1.

Sociodemographic and Clinical Characteristics of the TRS Sample and CNV Carriers

Characteristic	Entire Sample (n = 509)			CNV Carriers (n = 47)
	N	%		N	%
Sex
Male	334	65.6		32	68.1
Female	175	34.4		15	31.9
Ancestry
Hispanic	11	2.2		1	2.1
White	381	74.9		42	89.4
Black	98	19.3		4	8.5
Native American	1	0.2		—	—
Asian/Pacific Islander	6	1.2		—	—
Mixed ancestry	12	2.4		—	—
Primary chart DSM-IV diagnosisa
Schizophrenia (all subtypes)	238	46.8		23	48.9
Schizophrenia, disorganized	14	—		1	—
Schizophrenia, paranoid	119	—		12	—
Schizophrenia, undifferentiated	82	—		6	—
Schizophrenia, unspecified	23	—		4	—
Psychotic disorder NOS	14	2.7		3	6.4
Schizoaffective disorder	236	46.3		17	36.2
Bipolar disorder I with psychosis	15	2.9		3	6.4
Major depression with psychosis	6	1.2		1	2.1
Clozapine exposure	259	50.9		25	53.2
Adequate clozapine trial	175	34.3		14	29.8

	N	Mean	SD	N	Mean	SD
Age (years)b	509	53.6	13.2	47	54.5	13.1
Age at illness onset (years)c	479	21.2	8.7	45	22.6	11.7
Duration of illness (years)a	479	32.4	12.6	45	31.7	12.8
Duration of current hospitalization (years)	509	13.4	10.1	47	15.8	11.7
Total number of hospitalizationsa	509	8.1	8.0	47	8.4	9.0
Average GAF scorea, d	472	31.4	5.3	46	30.8	3.4
Most current GAF	484	32.3	6.3	45	31.1	5.4
Modified PANSS scores
Positive symptom score	363	19.1	5.7	33	21.0	4.8
Negative symptom score	363	17.0	6.7	33	16.2	5.5
Ammons quick test	341	86.5	15.5	27	88.1	14.4

Note: CNV, copy number variant; PANSS, positive and negative syndrome scale.

^aBased initially on medical records;

^bage at time of blood collection;

^cage at onset of psychotic symptoms (hallucinations or delusions);

^dGlobal Assessment of Functioning Scale—scores range from 1 (severe impairment) to 100 (extremely high functioning).