Skip to main content
. 2023 Jul 5;382:e073639. doi: 10.1136/bmj-2022-073639

Table 1.

Characteristics of cohort for all first ascertained SARS-CoV-2 infections in children and adolescents and by hospital admission type. Values are number (percentage) unless stated otherwise

Characteristics First ascertained SARS-CoV-2 infections Admission type
Total Positive SARS-CoV-2 test result only SARS-CoV-2 associated hospital admission Nosocomial Type C (incidental) Paediatric inflammatory multisystem syndrome Type A1 (caused by SARS-CoV-2 ) Type A2 (suspected caused by SARS-CoV-2) Type B1 (causal pathway) Type B2 (causal pathway)
Total No 3 226 535 3 197 305 29 230 380 7855 1790 9875 5330 2005 2000
Sex
Female 1 618 030 (50.1) 1 604 175 (50.2) 13 855 (47.4) 245 (64.5) 4000 (50.9) 715 (39.9) 4640 (47.0) 2465 (46.2) 865 (43.1) 920 (46.0)
Male 1 608 505 (49.9) 1 593 130 (49.8) 15 375 (52.6) 135 (35.5) 3855 (49.1) 1075 (60.1) 5235 (53.0) 2860 (53.7) 1135 (56.6) 1080 (54.0)
Age
Median (interquartile range) age (years) 11.4 (8.1-14.4) 11.5 (8.1-14.4) 5.5 (0.6-12.9) 7.4 (0.7-16.0) 10.6 (3.5-15.0) 7.6 (3.8-11.3) 1.3 (0.2-10.1) 4.1 (1.1-11.3) 1.2 (0.2-10.4) 9.5 (4.6-14.1)
Age group (years):
 <1 41 360 (1.2) 32 940 (1.0) 8415 (28.7) 120 (31.5) 1190 (15.2) 90 (5.1) 4590 (46.6) 1265 (23.7) 960 (47.8) 210 (10.4)
 1-4 273 785 (8.5) 268 070 (8.4) 5720 (19.6) 65 (17.1) 1150 (14.6) 505 (28.2) 1770 (17.9) 1610 (30.2) 290 (14.5) 330 (16.5)
 5-11 1 461 130 (45.3) 1 454 290 (45.5) 6840 (23.4) 20 (5.3) 2100 (26.7) 840 (46.9) 1545 (15.6) 1265 (23.7) 350 (17.5) 715 (35.8)
 12-15 1 044 335 (32.4) 1 039 080 (32.5) 5255 (18.0) 85 (22.4) 2125 (27.1) 305 (17.0) 1225 (12.4) 765 (14.4) 255 (12.7) 495 (24.8)
 16-17 405 925 (12.6) 402 925 (12.6) 3000 (10.3) 90 (23.7) 1290 (16.4) 50 (2.8) 745 (7.5) 425 (8.0) 150 (7.5) 250 (12.5)
Ethnic group
Asian or Asian British 274 870 (8.5) 270 510 (8.5) 4360 (15.0) 40 (10.5) 1000 (12.8) 355 (19.9) 1570 (16.0) 750 (14.1) 290 (14.5) 345 (17.2)
Black or black British 87 725 (2.7) 85 865 (2.7) 1860 (6.4) 25 (6.6) 435 (5.5) 235 (13.1) 565 (5.7) 245 (4.6) 135 (6.7) 220 (11.0)
Chinese 16 350 (0.5) 16 250 (0.5) 100 (0.3) 0 (0.0) 25 (0.3) 15 (0.8) 40 (0.4) 15 (0.3) <10 (<0.5) <10 (<0.5)
Mixed 127 880 (4.0) 126 325 (4.0) 1555 (5.3) 25 (6.6) 380 (4.8) 130 (7.3) 555 (5.6) 260 (4.9) 110 (5.5) 90 (4.5)
Other 59 990 (1.9) 59 050 (1.8) 940 (3.2) <10 (<2.6) 225 (2.9) 65 (3.6) 360 (3.6) 160 (3.0) 70 (3.5) 55 (2.8)
Unknown 36 915 (1.1) 36 685 (1.1) 235 (0.8) <10 (<2.6) 55 (0.7) 15 (0.8) 85 (0.9) 50 (0.9) 15 (0.7) 15 (0.8)
White 2 622 805 (81.3) 2 602 620 (81.4) 20 180 (69.0) 275 (72.4) 5735 (73.0) 975 (54.5) 6700 (67.8) 3850 (72.2) 1380 (68.8) 1265 (63.2)
Index of multiple deprivation fifth
1st (most deprived) 625 285 (19.3) 616 440 (19.3) 8845 (30.3) 95 (25.0) 2515 (32.0) 480 (26.8) 2945 (29.8) 1525 (28.7) 635 (31.6) 645 (32.1)
2nd 592 080 (18.4) 585 575 (18.3) 6505 (22.3) 100 (26.3) 1685 (21.5) 395 (22.1) 2195 (22.2) 1205 (22.6) 475 (23.7) 455 (22.8)
3rd 622 550 (19.3) 617 370 (19.3) 5180 (17.7) 75 (19.7) 1315 (16.7) 335 (18.7) 1820 (18.4) 940 (17.6) 365 (18.2) 335 (16.8)
4th 654 815 (20.3) 650 160 (20.3) 4655 (15.9) 60 (15.8) 1230 (15.7) 305 (17.0) 1595 (16.2) 880 (16.5) 280 (14.0) 310 (15.5)
5th (least deprived) 731 805 (22.7) 727 760 (22.8) 4045 (13.8) 50 (13.2) 1110 (14.1) 275 (15.4) 1320 (13.4) 780 (14.6) 250 (12.5) 255 (12.8)
Underlying health conditions
Health condition linked to clinical vulnerability 580 195 (18.0) 569 110 (17.8) 11 085 (37.9) 210 (55.3) 2550 (32.5) 515 (28.8) 3190 (32.3) 1730 (32.5) 1140 (56.9) 1745 (87.2)
Medical and developmental condition 939 965 (29.1) 923 690 (28.9) 16 275 (55.7) 280 (73.7) 3880 (49.4) 1020 (57.0) 4815 (48.8) 2795 (52.4) 1500 (74.8) 1990 (99.5)
Hospital admission features
Covid-19 positivity in window* - - 23 750 (81.3) 380 (100.0) 7005 (89.2) 130 (7.3) 8135 (82.4) 4615 (86.6) 1695 (84.5) 1795 (89.8)
Length of stay - - 2 (1 4) 93 (42 162) 2 (1 4) 6 (4 8) 2 (1 3) 2 (1 2) 3 (2 6) 2 (1 3)
Still in hospital - - 160 (0.5) 95 (25.0) 40 (0.5) 0 (0.0) <10 (<0.1) <10 (<0.2) 15 (0.7) <10 (<0.5)
ICU or HDU care - - 1710 (5.9) 105 (27.6) 255 (3.2) 535 (29.9) 315 (3.2) 95 (1.8) 320 (16.0) 85 (4.2)
Day patient - - 1805 (6.2) 0 (0.0) 815 (10.4) 85 (4.7) 70 (0.7) 95 (1.8) 75 (3.7) 665 (33.2)
Vaccination status 14 days before infection
Unvaccinated 2 878 355 (89.2) 2 850 515 (89.1) 27 840 (95.2) 340 (89.5) 7290 (92.8) 1760 (98.3) 9605 (97.2) 5115 (96.0) 1925 (96.0) 1805 (90.2)
First dose 297 030 (9.2) 296 010 (9.3) 1020 (3.5) 30 (7.9) 445 (5.7) 25 (1.4) 180 (1.8) 160 (3.0) 55 (2.7) 125 (6.2)
Second dose 48 875 (1.5) 48 560 (1.5) 315 (1.1) <10 (<2.6) 110 (1.4) <10 (<0.6) 65 (0.7) 45 (0.8) 25 (1.2) 60 (3.0)
Booster dose 2275 (0.1) 2220 (0.1) 55 (0.2) <10 (<2.6) 10 (0.1) 0 (0.0) 25 (0.3) <10 (<0.2) <10 (<0.5) <10 (<0.5)
Variant period
Original 127 205 (3.8) 124 770 (3.8) 2450 (8.3) 35 (9.2) 730 (9.4) 230 (12.8) 690 (6.9) 430 (8.1) 155 (7.8) 175 (8.7)
Original-alpha 101 885 (3.2) 100 435 (3.1) 1450 (5.0) 35 (9.2) 410 (5.2) 105 (5.9) 445 (4.5) 240 (4.5) 120 (6.0) 95 (4.7)
Alpha 158 960 (4.9) 155 660 (4.9) 3300 (11.3) 60 (15.8) 895 (11.4) 425 (23.7) 945 (9.6) 575 (10.8) 185 (9.2) 210 (10.4)
Alpha-delta 15 525 (0.5) 15 260 (0.5) 260 (0.9) <10 (<2.6) 65 (0.8) 35 (2.0) 75 (0.8) 50 (0.9) 25 (1.2) 15 (0.8)
Delta 1 612 630 (50.0) 1 601 445 (50.1) 11 185 (38.3) 95 (25.0) 2945 (37.5) 725 (40.5) 3995 (40.5) 1915 (35.9) 820 (40.9) 695 (34.8)
Delta-omicron 195 475 (6.1) 194 125 (6.1) 1345 (4.6) 25 (6.6) 340 (4.3) 70 (3.9) 455 (4.6) 240 (4.5) 100 (5.0) 115 (5.8)
Omicron 1 014 855 (31.5) 1 005 610 (31.5) 9240 (31.6) 125 (32.9) 2470 (31.4) 200 (11.2) 3270 (33.1) 1880 (35.3) 600 (29.9) 695 (34.8)
Mortality
Death 295 (0.0) 130 (0.0) 165 (0.6) <10 (<2.6) 30 (0.4) <10 (<0.6) 60 (0.6) 15 (0.3) 30 (1.5) 20 (1.0)
Hospital death: 70 (0.0) <10 (0.0*) 65 (0.2) <10 (<2.6) 10 (0.1) 0 (0.0) 30 (0.3) <10 (<0.2) 15 (0.7) <10 (<0.5)
 Covid-19 or PIMS-TS related 70 (0.0) 20 (0.0) 55 (0.2) <10 (<2.6) <10 (<0.1) 0 (0.0) 35 (0.4) <10 (<0.2) <10 (<0.5) <10 (<0.5)
 Covid-19 or PIMS-TS underlying 55 (0.0) 15 (0.0) 40 (0.1) 0 (0.0) <10 (<0.1) 0 (0.0) 30 (0.3) <10 (<0.2) <10 (<0.5) 0 (0.0)
 Covid-19 or PIMS-TS related hospital death 40 (0.0) 0 (0.0) 40 (0.1) <10 (<2.6) <10 (<0.1) 0 (0.0) 25 (0.3) <10 (<0.2) <10 (<0.5) <10 (<0.5)
 Covid-19 or PIMS-TS underlying hospital death 30 (0.0) 0 (0.0) 30 (0.1) 0 (0.0) <10 (<0.1) 0 (0.0) 25 (0.3) <10 (<0.2) <10 (<0.5) 0 (0.0)

PIMS-TS=paediatric Inflammatory multisystem syndrome with a temporal association with SARS-CoV-2.

*

Counted only when test occurred 14 days before date of admission up to discharge—this window defines an admission as SARS-CoV-2-related, and it could be (but equally may not be the sole) reason for the inclusion of these participants in the applicable group.