Table 2.
Number (%) of participants with underlying health conditions for first ascertained SARS-CoV-2 infections, shown for children and adolescents not admitted to hospital, those with SARS-CoV-2 associated hospital admissions, those requiring ICU or HDU care, and those who died with covid-19 or paediatric inflammatory multisystem syndrome listed as one of the causes
| Variables | First ascertained SARS-CoV-2 infections | ICU/HDU subset | Covid-19 or PIMS-TS related death | ||
|---|---|---|---|---|---|
| Total | Positive SARS-CoV-2 test result only | Covid-19 associated hospital admission | |||
| Total No of participants in group | 3 226 535 | 3 197 305 | 29 230 | 1710 | 70 |
| Health condition linked to greater vulnerability | |||||
| Total No with health condition | 580 195 (18.0) | 569 110 (17.8) | 11 085 (37.9) | 835 (48.8) | 55 (78.6) |
| Health conditions: | |||||
| Cancer (excluding benign tumours) | 4515 (0.1) | 3495 (0.1) | 1020 (3.5) | 40 (2.3) | <10 (<14.3) |
| Blood disorders and immune deficiencies | 11 765 (0.4) | 10 665 (0.3) | 1095 (3.7) | 70 (4.1) | <10 (<14.3) |
| Endocrine conditions | 20 985 (0.7) | 19 570 (0.6) | 1420 (4.9) | 125 (7.3) | 15 (21.4) |
| Severe neurological and developmental conditions | 119 910 (3.7) | 117 140 (3.7) | 2770 (9.5) | 265 (15.5) | 35 (50.0) |
| Hypertension, cardiac valve disorders, and cardiomyopathy | 10 765 (0.3) | 9625 (0.3) | 1140 (3.9) | 195 (11.4) | 10 (14.3) |
| Severe respiratory diseases | 399 610 (12.4) | 394 655 (12.3) | 4950 (16.9) | 260 (15.2) | 20 (28.6) |
| Digestive, liver, and renal diseases | 6605 (0.2) | 5810 (0.2) | 790 (2.7) | 35 (2.0) | <10 (<14.3) |
| Arthritis and connective tissue diseases | 8870 (0.3) | 8490 (0.3) | 380 (1.3) | 20 (1.2) | 0 (0.0) |
| Congenital syndromes and anomalies | 68 875 (2.1) | 65 930 (2.1) | 2950 (10.1) | 375 (21.9) | 35 (50.0) |
| Obesity (age >16 years) | 6245 (0.2) | 6020 (0.2) | 220 (0.8) | <10 (<0.6) | 0 (0.0) |
| Pregnancy | 4425 (0.1) | 4110 (0.1) | 315 (1.1) | 0 (0.0) | 0 (0.0) |
| Medical and developmental underlying health conditions identified by the study team | |||||
| Total No with health condition | 907 960 (28.1) | 892 110 (27.9) | 15 850 (54.2) | 1315 (76.9) | 65 (92.9) |
| Health condition: | |||||
| Cancer and neoplasms (excluding benign tumours) | 5575 (0.2) | 4465 (0.1) | 1110 (3.8) | 55 (3.2) | <10 (<14.3) |
| Blood disorders and immune deficiencies | 23 585 (0.7) | 21 225 (0.7) | 2360 (8.1) | 170 (9.9) | <10 (<14.3) |
| Endocrine conditions | 101 105 (3.1) | 97 610 (3.1) | 3495 (12.0) | 320 (18.7) | 30 (42.9) |
| Neurological and developmental conditions | 256 000 (7.9) | 250 045 (7.8) | 5955 (20.4) | 535 (31.3) | 50 (71.4) |
| Respiratory conditions | 489 645 (15.2) | 482 900 (15.1) | 6745 (23.1) | 400 (23.4) | 40 (57.1) |
| Hypertension and heart disease (congenital and acquired) | 325 870 (10.1) | 320 770 (10.0) | 5100 (17.4) | 630 (36.8) | 35 (50.0) |
| Digestive and liver conditions | 49 695 (1.5) | 47 705 (1.5) | 1985 (6.8) | 145 (8.5) | 10 (14.3) |
| Muscle, skin, and arthritis | 55 940 (1.7) | 53 835 (1.7) | 2105 (7.2) | 220 (12.9) | 30 (42.9) |
| Renal and genitourinary conditions | 88 410 (2.7) | 86 425 (2.7) | 1985 (6.8) | 140 (8.2) | 15 (21.4) |
| Prematurity and low birth weight | 31 595 (1.0) | 29 155 (0.9) | 2440 (8.3) | 390 (22.8) | 10 (14.3) |
| Evidence of obesity | 83 405 (2.6) | 81 980 (2.6) | 1425 (4.9) | 80 (4.7) | <10 (<14.3) |
| Evidence of recent or current pregnancy | 4425 (0.1) | 4110 (0.1) | 315 (1.1) | 0 (0.0) | 0 (0.0) |
HDU=high dependency unit; ICU=intensive care unit; PIMS-TS=paediatric Inflammatory multisystem syndrome with a temporal association with SARS-CoV-2.