PUL-encoded proteins show OMV enrichment except for Bt grown in mucin. PUL-encoded proteins were identified and classified as OM-enriched (OMV/OM fold change <−1, M column, colored in orange), OMV-enriched (OMV/OM fold change >1, V column, colored in green), or unclassified (OMV/OM fold change between −1 and 1, colored in gray). Circle size represents the number of identified proteins for each PUL. Main representative PULs are shown (complete PUL dataset in SI Appendix, Fig. S9).