Table 1.
pID Patients | Healthy Controls | p-value | |
---|---|---|---|
Sociodemographics: | |||
Age (years) | 58.1 (12.2) | 55.3 (10.0) | p = 0.19 |
Gender (n. male/ female) | 19 / 3 | 16 / 6 | p = 0.13 |
Education (n. low/medium/high) | 3 / 12 / 7 | 1 / 15 / 6 | p = 0.25 |
Estimated intelligence quotient (MWTB) | 112.6 (12.7) | 118.4 (14.2) | p = 0.08 |
Self-assessment of anxiety and depression: | |||
HADS Anxiety (max. 21 points) | 8.9 (5.1) | 3.7 (2.5) | p = <0.01* |
HADS Depression (max. 21 points) | 7.5 (4.5) | 3.3 (2.6) | p = <0.01* |
Subjective sleep quality: | |||
PSQI (max. 21 points) | 14.3 (3.2) | 4.8 (2.8) | p = <0.01* |
ISI (max. 28 points) | 18.5 (4.8) | 4.0 (4.1) | p = <0.01* |
Objective polysomnographic sleep quality: | |||
Sleep Efficiency (%) | 58.9 (17.8); CI: 50.97, 66.73 | ||
Sleep-onset latency (minutes) | 52.2 [86.3]; CI:41.57, 96.11 | ||
Wake after sleep onset (minutes) | 132.4 (52.0); CI:109.33, 155.41 | ||
Sleep-stage transition index (/hour) | 14.5 [6.6]; CI: 13.8, 20.22 | ||
Arousal index (/hour) | 18.9 [14.9]; CI: 15.5, 25.13 | ||
Apnea/Hypopnea index (/hour) | 2.4 [4.3]; CI: 1.17, 8.29 | ||
Periodic Limb Movement index (/hour) | 2.4 [6.1] CI: 2.21, 7.23 | ||
Sleep stage distribution (% of Time In Bed): | |||
Time Awake | 41.2 (17.8); CI:33.24, 49.06 | ||
Light sleep | 34.2 (14.6); CI:27.76, 40.64 | ||
Deep sleep | 13.9 (7.4); CI:10.60, 17.18 | ||
REM sleep | 10.4 (5.6); CI:7.98, 12.90 |
Notes: Mean and standard deviation (in parentheses) given for normally distributed data. Medians and interquartile ranges (in square brackets) and are presented for non-normally distributed data. CI: 95% Confidence Intervals are given for polysomnographic data. Gender and education expressed as number of participants. An asterisk marks significant differences.
Abbreviations: n., number of; pID, persistent Insomnia Disorder; MWTB, Mehrfachwahl Wortschatz Intelligenz Test B; PSQ, Pittsburgh Sleep Quality Index; ISI, Insomnia Severity Index; HADS, Hospital Anxiety and Depression Scale; REM, Rapid Eye Movement.