Table 1.
Correlates of Severe Acute Respiratory Syndrome Coronavirus 2 Transmission in Households
| Correlate | Univariable | Multivariable | Multivariable Whole Household Enrolled |
|||
|---|---|---|---|---|---|---|
| OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | |
| VL (in the source at enrollment), log10 copies/mL | 1.37 | (1.06–1.76) | 1.40 | (1.07–1.85) | 1.54 | (1.08–2.19) |
| Contact shares bedroom with index case | 2.88 | (1.32–6.32) | 2.99 | (1.35–6.71) | 3.80 | (1.34–10.68) |
| Contact age (10-y increase) | 1.19 | (.97–1.49) | … | … | … | … |
| Contact is male | 1.16 | (.55–2.45) | … | … | … | … |
| Contact identifies as Hispanic/Latino ethnicity | 1.30 | (.62–2.73) | … | … | … | … |
| Source identifies as Hispanic/Latino ethnicity | 1.25 | (.58–2.68) | 1.85 | (.81–4.19) | 1.33 | (.46–3.81) |
| Does not wear a face mask indoors (excluding within the household) | 1.68 | (.58–4.85) | … | … | … | … |
| No. of household members positive (excluding index case) 0 1 ≥2 | … 1.51 1.35 | … (.57–4.01) (.36–5.02) | … … … | … … … | … … … | … … … |
| ≥2 symptomatic COVID-19 cases in the household (excluding index case) | 1.11 | (.40–3.06) | … | … | … | … |
| BMI ≥30 kg/m2 (contact) | 1.25 | (.59–2.70) | … | … | … | … |
| BMI ≥30 kg/m2 (source) | 1.86 | (.85–4.07) | … | … | … | … |
| South-central region of United States | 1.89 | (.87–4.15) | … | … | … | … |
| Source is seropositive at baseline | 0.55 | (.21–1.41) | 0.96 | (.35–2.66) | 1.15 | (.35–3.80) |
| Source randomized to placebo arm | 0.95 | (.42–2.17) | … | … | … | … |
Significant correlates (95% CI excludes 1.00) are shown in bold.
Abbreviations: BMI, body mass index; CI, confidence interval; COVID-19, coronavirus disease 2019; OR, odds ratio; VL, viral load.