Figure 5.

Chromatin accessibility at single nucleus level of muscle-resident cells upon denervation

(A) UMAP embedding of snATAC-seq data after integration, colored according to our scRNA-seq data.

(B) Table illustrating the number of nuclei assigned to each muscle-resident cell population and the number of differential accessibility regions (DARs) between DEN5d and CTR.

(C) Histogram of the number of DARs overlapping promoters (red, UP) or non-promoter (enhancer, in blue, DOWN) regions, per cell type.

(D–F) UMAP embedding of snATAC-seq data, showing the predicted gene expression profile for Thy1 (CD90) (D), Ngf (E) ,and Ngfr (F), either dim (blue) or bright (red).