Table 2.

shows the Pearson’s correlation coefficients (r) for the relationships between V_T and self-reported alcohol use in 27 AUD.

	Prior to PET scans	30 days prior to enrollment
Region V_T	Number of days abstinent	Drinking days	Drinks per drinking day
Amygdala	0.282	− 0.548^**	− 0.562^**
Hippocampus	0.459^*	− 0.544^**	− 0.586^**
Midbrain	0.413^*	− 0.472^*	− 0.533^**
Ventral Striatum	0.415^*	− 0.568^**	− 0.560^**
Caudate	0.403^*	− 0.474^*	− 0.520^*
Putamen	0.403^*	− 0.526^*	− 0.542^**
Dorsolateral prefrontal cortex	0.366	− 0.530^**	− 0.548^**
Orbitofrontal cortex	0.374	− 0.598^**	− 0.593^**
Medial prefrontal cortex	0.361	− 0.529^*	− 0.542^**
Anterior Cingulate cortex	0.401^*	− 0.547^**	− 0.556^**
Cerebellum	0.374	− 0.445^*	− 0.530^**

Significant positive associations between V_T and abstinent days before PET were present in six out of eleven ROIs (Figure S1). Significant negative associations between V_T and number of drinking days (Figure S2), and mean drinks/drinking day (Figure S3) in the past thirty days prior to enrollment were present in all ROIs.

p ≤ 0.05

^**

Bonferroni corrected p ≤ 0.00454.