Table 1.
Demographic and Clinical Characteristics of Patients Who Were Tested for SARS-CoV-2 in the Cleveland Clinic Health System During the Delta- and Omicron-Predominant Periods
| Variable | Total | Dose 2 | Dose 3 | Other Vaccination |
SARS-CoV-2 Positive | SARS-CoV-2 Positive Death | ||
|---|---|---|---|---|---|---|---|---|
| <180 d | ≥180 d | <180 d | ≥180 d | |||||
| All | 295 691 | 27 861 | 75 545 | 51 479 | 6834 | 17 593 | 76 350 | 1765 |
| Time period | ||||||||
| ȃDelta predominant | 171 249 (58) | 19 590 (70) | 46 741 (62) | 16 008 (31) | 3676 (54) | 9655 (55) | 28 998 (38) | 879 (50) |
| ȃOmicron predominant | 124 442 (42) | 8271 (30) | 28 804 (38) | 35 471 (69) | 3158 (46) | 7938 (45) | 47 352 (62) | 886 (50) |
| Location | ||||||||
| ȃOhio | 255 714 (86) | 24 706 (89) | 66 321 (88) | 44 145 (86) | 5600 (82) | 15 074 (86) | 69 130 (91) | 1613 (91) |
| ȃOther | 39 977 (14) | 3155 (11) | 9224 (12) | 7334 (14) | 1234 (18) | 2519 (14) | 7220 (9) | 152 (9) |
| Age, y | ||||||||
| ȃ <65 | 220 908 (75) | 24 291 (87) | 52 319 (69) | 26 653 (52) | 3034 (44) | 13 246 (75) | 61 927 (81) | 1613 (91) |
| ȃ ≥65 | 74 783 (25) | 3570 (13) | 23 226 (31) | 24 826 (48) | 3800 (56) | 4347 (25) | 14 423 (19) | 152 (8.6) |
| Sex | ||||||||
| ȃFemale | 173 286 (59) | 17 400 (62) | 46 665 (62) | 30 950 (60) | 3917 (57) | 10 216 (58) | 44 859 (59) | 788 (45) |
| ȃMale | 122 405 (41) | 10 461 (38) | 28 880 (38) | 20 529 (40) | 2917 (43) | 7377 (42) | 31 491 (41) | 977 (55) |
| Race and ethnicity | ||||||||
| ȃWhite, non-Hispanic | 201 158 (68) | 17 833 (64) | 55 920 (74) | 40 526 (79) | 5595 (82) | 11 820 (67) | 50 949 (67) | 1223 (70) |
| ȃBlack, non-Hispanic | 44 319 (15) | 5209 (19) | 8807 (12) | 4558 (9) | 564 (8) | 3085 (18) | 12 456 (16) | 355 (20) |
| ȃHispanic | 18 628 (6) | 2418 (9) | 4471 (6) | 2343 (4) | 263 (4) | 1161 (6) | 4750 (6) | 59 (3) |
| ȃOther/unknown | 31 586 (11) | 2401 (8) | 6347 (8) | 4052 (8) | 412 (6) | 1527 (9) | 8195 (11) | 128 (7) |
| Prior infection | ||||||||
| ȃNo | 272 759 (92) | 25 056 (90) | 69 631 (92) | 48 145 (94) | 6412 (94) | 15 881 (90) | 72 421 (95) | 1726 (98) |
| ȃYes | 22 932 (8) | 2805 (10) | 5914 (8) | 3334 (6) | 422 (6) | 1712 (10) | 3929 (5) | 39 (2) |
| Smoking | ||||||||
| ȃNever | 159 878 (54) | 15 981 (57) | 42 854 (57) | 29 586 (57) | 3678 (54) | 9019 (51) | 41 224 (54) | 592 (34) |
| ȃCurrent | 35 257 (12) | 4304 (16) | 7854 (10) | 3481 (7) | 622 (9) | 3030 (17) | 8551 (11) | 199 (11) |
| ȃUnknown | 100 556 (34) | 7576 (27) | 24 837 (33) | 18 412 (36) | 2534 (37) | 5544 (32) | 26 575 (35) | 974 (55) |
| Respiratory conditionsa | ||||||||
| ȃNo | 226 889 (77) | 20 639 (74) | 56 619 (75) | 37 435 (73) | 4768 (70) | 12 869 (73) | 60 375 (79) | 1143 (65) |
| ȃYes | 68 802 (23) | 7222 (26) | 18 926 (25) | 14 044 (27) | 2066 (30) | 4724 (27) | 15 975 (21) | 622 (35) |
| Nonrespiratory conditionsa | ||||||||
| ȃNo | 115 716 (39) | 10 310 (37) | 22 577 (30) | 11 670 (23) | 1198 (18) | 5615 (32) | 32 886 (43) | 180 (10) |
| ȃYes | 179 975 (61) | 17 551 (63) | 52 968 (70) | 39 809 (77) | 5636 (82) | 11 978 (68) | 43 464 (57) | 1585 (90) |
| Immunocompromised condition | ||||||||
| ȃNo | 273 933 (93) | 25 891 (93) | 69 813 (92) | 45 774 (89) | 5938 (87) | 15 762 (90) | 71 822 (94) | 1127 (64) |
| ȃYes | 21 758 (7) | 1970 (7) | 5732 (8) | 5705 (11) | 896 (13) | 1831 (10) | 4528 (6) | 638 (36) |
Data are No. (%).
Respiratory conditions are chronic pulmonary disease and pulmonary circulation disease. Nonrespiratory conditions are congestive heart failure, valvular disease, peripheral vascular disease, paralysis, other neurological disorders, diabetes, hypothyroidism, renal failure, liver disease, peptic ulcer disease and bleeding, lymphoma, metastatic cancer, solid tumor without metastasis, rheumatoid arthritis/collagen vascular diseases, coagulopathy, obesity, fluid and electrolyte disorders, chronic blood loss anemia, deficiency anemias, alcohol abuse, drug abuse, psychoses, and depression. Elixhauser Comorbidity Software version 3.7 was used to extract the data. The definitions and ICD-10 codes can be found at: https://www.hcup-us.ahrq.gov/toolssoftware/comorbidity/comorbidity.jsp.