Table 3.

Overall Relative Risks of Infection With the Delta or Omicron Variant and Progression to Death Associated with COVID-19 Vaccination, Prior SARS-CoV-2 Infection, and Monoclonal Antibody Therapy

Variable	Delta Variant	Omicron Variant
Vaccination status
ȃUnvaccinated	Reference	Reference
ȃDose 2 ≥180 d	0.21 (.17–.25)	0.54 (.41–.65)
ȃDose 2 <180 d	0.12 (.05–.16)	0.20 (.05–.32)
ȃDose 3 ≥180 d	0.08 (.02–.13)	0.17 (.08–.25)
ȃDose 3 <180 d	0.04 (.02–.06)	0.10 (.08–.13)
ȃOther vaccination	0.44 (.29–.57)	0.54 (.38–.67)
Prior infection	0.04 (.00–.08)	0.27 (.11–.37)
Monoclonal antibodies	0.45 (.29–.57)	0.50 (.28–.74)

Shown in parentheses are 95% confidence intervals based on 200 bootstrap samples.