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. 2023 Jun 5;8(4):700–712. doi: 10.1093/jalm/jfad024

Table 4.

Weighted proportion of healthy individuals with elevated NT-proBNP.

Proportion with NT-proBNP at or above 125 or 450 ng/L (95% confidence interval)
Age category (years) Sex 125 ng/L 450 ng/L
1 Male 34.2% (17.5, 53.2)
Female 28.8% (12.9, 48.0)
2 to 5 Male 15.7% (9.8, 22.7)
Female 17.5% (11.8, 24.2)
6 to 11 Male 14.3% (10.3, 18.7)
Female 12.5% (9.2, 16.1)
12 to 15 Male 3.3% (2.1, 4.8)
Female 3.5% (2.1, 5.3)
16 to 19 Male 0.1% (0.0, 0.3)
Female 2.5% (1.1, 4.3)
20 to 29 Male 1.1% (0.1, 3.1)
Female 8.8% (5.9, 12.3)
30 to 39 Male 2.0% (0.4, 4.8)
Female 5.9% (2.6, 10.4)
40 to 49 Male 3.1% (0.3, 8.6)
Female 14.7% (8.6, 22.1)
50 to 59 Male 6.5% (1.0, 16.1)
Female 22.7% (13.4, 33.8)
60 to 69 Male 15.1% (4.1, 31.4)
Female 22.5% (7.5, 42.5)
70 to 79 Male 49.9% (14.3, 85.6) 23.5% (0.3, 66.5)
Female 52.6% (14.0, 89.4) 19.5% (0.2, 67.3)
80+ Male 69.3% (34.6, 94.7) 6.4% (0.3, 28.9)
Female 83.6% (46.4, 100.0) 8.8% (2.2, 46.8)

This table displays the survey weighted proportion of healthy individuals from NHANES survey cycles 1999–2004, partitioned by sex and age category, with an NT-proBNP measurement equal to or above the preselected values of 125 and 450 ng/L. 95% confidence intervals were calculated using the variance-stabilizing arcsine square root transformation for the binomial distribution, subsequently expressed on the probability scale.