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. 2023 May 11;51(W1):W379–W386. doi: 10.1093/nar/gkad375

Figure 2.

Figure 2.

ADORA2A- (top panels) and PITX3-based (bottom panels) MiniPromoters designed either using OnTarget (left panels) or by manually identifying and combining CRRs potentially regulating the expression of each gene (right panels). MiniPromoters were characterized in mice for their ability to drive specific expression in the striatum (ADORA2A) or the substantia nigra (PITX3) using rAAV vectors (Methods). SN, substantia nigra; Str, striatum. Green, anti-GFP; blue, Hoechst.