Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 7;26(7):107058. doi: 10.1016/j.isci.2023.107058

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 The Authors.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Association of TMErisk with cellular and molecular signatures

(A) TME-related Functional enrichment was performed by the compareCluster function. The x-axis represents different selected genes used for conducting enrichment analysis. The left facet panel shows the enriched pathways for genes up-regulated in the high-TMErisk group, and the right facet panel shows the enriched pathways for genes up-regulated in the low-TMErisk group.

(B) The heatmap shows the normalized infiltration abundance of immune and stromal cells that estimated by CIBERSORT, EPIC and xCell algorithms. In the Wilcoxon test results, the orange asterisks indicate cells significantly enriched in the low-TMErisk group, and the lightgreen asterisks indicate cells significantly enriched in the high-TMErisk group. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001; ns, not significant. See also Figures S5–S8.