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. 2023 Jun 26;93:104678. doi: 10.1016/j.ebiom.2023.104678

Fig. 5.

Fig. 5

Antigen-specific TNF-producing T cell subsets correlate with circulating IgG levels. (a) Spearman correlations were assessed between ESAT-6/CFP-10 specific COMPASS subsets and PFS and ESAT-6/CFP-10-specific IgG level and sialylation, for RSTR (n = 21) and LTBI (n = 9) subjects overlapping between COMPASS and Luminex datasets. Color of heatmap indicates degree of correlation coefficient from −1 to 1. ∗p < 0.05, ∗∗p < 0.01. (b) correlations were measured between Ag85A/Ag85B/TB10.4 -specific COMPASS subsets and Ag85-specific IgG level and sialylation. (c) Correlations were assessed between M.tb lysate specific COMPASS subsets and PPD-specific IgG level and Fc sialylation. (d) Correlations were assessed between Staphylococcal enterotoxin B-specific COMPASS subsets and influenza hemagglutinin-specific IgG level and Fc sialylation.