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. 2023 Jun 21;11:1162654. doi: 10.3389/fped.2023.1162654

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© 2023 Maia, Miranda, Geraldo, Sampaio, Ramaglia, Tortora, Severino and Rossi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Normal appearing pituitary gland and sella in a 6-year-old girl. Brain MRI including coronal (A) and sagittal (C) T1WI as well as coronal (B) and sagittal (D) T2WI reveal a normal sized sella turcica as well as regular volume and morphology of the adenohypophysis according to age and gender (white arrowhead). Note symmetry and homogeneous signal intensity of the gland and flattened superior border (empty white arrowhead). The pituitary stalk is in the midline and presents regular thickness (asterisks). The spontaneous T1 hyperintensity of the neurohypophysis, related to vasopressin storage, is better depicted in sagittal imaging in the posterior aspect of the sella turcica (black arrowhead). Also note normal permeability of the suprasellar cistern and regular lateral concavity of the cavernous sinuses (white arrows). Coronal (E) and sagittal (F) T1WI after gadolinium injection reveal normal homogeneous enhancement of the pituitary gland (empty black arrowhead), pituitary stalk (hashtag), and cavernous sinus (empty white arrows) due to absence of blood brain barrier. MR imaging should also include pre (G) and post-contrast volumetric T1 MPRAGE imaging not shown) for morphological characterization of brain as well as better depiction of focal areas of hypo-enhancement within the pituitary gland or characterization of other sellar/suprasellar masses, respectively. Sagittal 3D T2-weighted sequences (e.g., CISS) (H) are useful in the anatomical characterization of the sellar region including pituitary gland as well as other midline structures and cystic lesions.