Figure 3.

Correlations between circulating lipid features associated with stricturing or internal penetrating Crohn’s disease patients vs control subjects. Positive correlations (r > 0.4) existing between the 73 B2/B3-associated features [P < 1 × 10-4 and │log₂(fold change)│] in IBDGC-2 are illustrated using Fruchterman-Reingold algorithm, where the clusters with identified analytes are labeled A–E. Bond thickness corresponds to the strength of correlation between features. Circled features with bold ID are the 9 components of the classification model (see Figure 5). For expansions of the lipid subclasses, see Figure 2.