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. 2023 Mar 8;43(4):704–714. doi: 10.19852/j.cnki.jtcm.20230308.001

Figure 2. Effects of EA stimulation on the expressions of PKA-Cβ, p-CREB, BDNF, and TrkB.

Figure 2

A: PKA-Cβ; B: p-CREB; C: BDNF; D: TrkB. PKA-Cβ: catalytic subunits Cβ of cyclic AMP dependent protein kinase; Normal: control group, Model: injected with PCPA, Shenmen (HT7): model mice with EA at Shenmen (HT7), Baihui (GV20): model mice with EA at Baihui (GV20), Sanyinjiao (SP6): model mice with EA at Sanyinjiao (SP6), Combined: model mice with EA at Shenmen (HT7), Baihui (GV20) and Sanyinjiao (SP6). p-CREB: phosphorylated cAMP-responsive element-binding protein; PCPA: para-chlorophenylalanine; BDNF: brain-derived neurotrophic factor; TrkB: tyrosine kinase receptor B. aP < 0.01, compared with the normal group; bP < 0.05, compared with the model group; cP < 0.05, compared with the Sanyinjiao (SP6) group; dP < 0.01, compared with the model group; eP < 0.05, compared with the Baihui (GV20) group; fP < 0.05, compared with the Shenmen (HT7) group; gP < 0.05, compared with the normal group (n = 6). Data are presented as mean ± standard deviation. Statistics by one-way repeated measures analysis of variance followed by the least significant difference test.