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. 2023 Jun 22;93:104662. doi: 10.1016/j.ebiom.2023.104662

Fig. 1.

Fig. 1

Comparison of baseline serum NfL distributions in (a) persons with RMS in OPERA I (n = 701) and II (n = 720); (b) persons with RMS pooled from OPERA I/II (n = 1421), persons with PPMS from ORATORIO (n = 596), and HDs (n = 118); (c) persons with RMS (n = 560) or PPMS (n = 141) with acute disease activity grouped by study; and (d) persons with RMS (n = 688) or PPMS (n = 464) without acute disease activity grouped by study. Statistical comparisons were conducted with the Kolmogorov–Smirnov test. HD = healthy donor; Gd = gadolinium; NfL = neurofilament light; ns = not significant; PPMS = primary progressive multiple sclerosis; RMS = relapsing multiple sclerosis. ∗∗∗P < 0.0001.