Fig. 1.

CYLD expression in normal human skin. CYLD is expressed in diverse human skin cells. Here, we show expression levels in individual skin cell types as measured by single-cell RNA sequencing from the Human Protein Atlas database (Uhlen et al., 2010) (https://www.proteinatlas.org/ENSG00000083799-CYLD/single+cell+type). The blue-to-red gradient represents lowest-to-highest transcripts per million (TPM). The highest level of CYLD expression was measured in suprabasal keratinocytes, Langerhans cells and T-cells (red); the lowest expression of CYLD was found in melanocytes (blue).