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. 2023 May 26;42(6):112525. doi: 10.1016/j.celrep.2023.112525

Figure 3.

Figure 3

Neutrophil transcriptional states from control and COPD patients correspond to distinct phenotypes

(A) Experimental design and analysis pipeline.

(B) UMAP representation of 4,072 neutrophils from three controls and three COPD patients.

(C) Heatmap of the top 5 marker genes for each neutrophil state. Each column represents the scaled average normalized expression per patient.

(D) Violin plots of neutrophil state-specific protein markers.

(E) Violin plots of differentially expressed protein markers between control and COPD patients for blood neutrophil states. Statistical analysis was performed with the MAST algorithm, ∗p < 0.05, ∗∗∗p < 0.001.