Table 3.

Multivariate analysis of non-HDL-C/HDL-C ratio and 1-year risk of recurrent stroke in patients with NICE stratified by age of 65 years

Subgroup	Variable	Overall	Event, n%	Crude Model HR(95%CI)	P value	Adjusted Model HR(95%CI)	P value
Age < 65 year
	Non-HDL-C/HDL-C ratio, per 1 unit increase	833	19(2.3)	0.91(0.63 ~ 1.32)	0.61	1.23(0.77 ~ 1.95)	0.391
	Non-HDL-C/HDL-Cratio quartile
	Q1	178	5 (2.8)	Ref.		Ref.
	Q2	201	6 (3)	1.08 (0.33 ~ 3.53)	0.902	1.98(0.43 ~ 9.15)	0.384
	Q3	206	4 (1.9)	0.69 (0.19 ~ 2.59)	0.587	1.40(0.26 ~ 7.53)	0.697
	Q4	248	4 (1.6)	0.57 (0.15 ~ 2.13)	0.406	1.36(0.22 ~ 8.37)	0.744
	P for trend				0.31		0.854
Age≥65 year
	Non-HDL-C/HDL-C ratio, per 1 unit increase	826	39(4.7)	1.33(1.02 ~ 1.74)	0.038	1.64(1.18 ~ 2.27)	0.003
	Non-HDL-C/HDL-C ratio quartile
	Q1	237	6 (2.5)	Ref.		Ref.
	Q2	213	9 (4.2)	1.65 (0.59 ~ 4.64)	0.341	2.02(0.64 ~ 6.39)	0.229
	Q3	209	12 (5.7)	2.26 (0.85 ~ 6.03)	0.102	3.21(1.05 ~ 9.83)	0.041
	Q4	167	12 (7.2)	2.85 (1.07 ~ 7.60)	0.036	4.24(1.3 ~ 13.85)	0.017
	P for trend				0.025		0.011

Notes: Crude adjust none; adjusted for sex; smoking, drinking, prior stroke, pneumonia, NIHSS score at admission, BMI, ALT, triglyceride, FBG, alkaline phosphatase, platelet count, blood urea nitrogen, hypertension, atrial fibrillation, and diabetes mellitus. Abbreviations: BMI, body mass index; FBG, fasting blood glucose; NIHSS, national institutes of health stroke scale; ALT, alanine aminotransferase; HR, hazard ratio; CI, confidence interval; and Q, quartiles. Q1: <2.256, Q2:2.256–2.939, Q3: 2.940–3.749, Q4: ≥3.750