Table 1.
Baseline demographics and comorbidities
| All patients with gout | Patients with no admissions | Patients with one admission | Patients with multiple admissions | |
|---|---|---|---|---|
| n = 292 270 | n = 284 551 | n = 6805 | n = 914 | |
| Age at diagnosis | 62 (16) | 61 (16) | 67 (16) | 66 (16) |
| Sex | ||||
| Male | 216 630 (74.1%) | 211 066 (74.2%) | 4881 (71.7%) | 683 (74.7%) |
| Number of comorbidities at diagnosis | 1.6 (1.4) | 1.6 (1.4) | 2.3 (1.6) | 2.5 (1.7) |
| CKD stage 3–5 | ||||
| No | 214 809 (73.5%) | 210 617 (74.0%) | 3748 (55.1%) | 444 (48.6%) |
| Yes | 77 461 (26.5%) | 73 934 (26.0%) | 3057 (44.9%) | 470 (51.4%) |
| Hypertension | ||||
| No | 149 422 (51.1%) | 146 398 (51.4%) | 2681 (39.4%) | 343 (37.5%) |
| Yes | 142 848 (48.9%) | 138 153 (48.6%) | 4124 (60.6%) | 571 (62.5%) |
| Diabetes mellitus | ||||
| No | 252 057 (86.2%) | 246 066 (86.5%) | 5309 (78.0%) | 682 (74.6%) |
| Yes | 40 213 (13.8%) | 38 485 (13.5%) | 1496 (22.0%) | 232 (25.4%) |
| Ischaemic heart disease | ||||
| No | 243 893 (83.4%) | 238 311 (83.7%) | 4957 (72.8%) | 625 (68.4%) |
| Yes | 48 377 (16.6%) | 46 240 (16.3%) | 1848 (27.2%) | 289 (31.6%) |
| Heart failure | ||||
| No | 271 441 (92.9%) | 265 105 (93.2%) | 5624 (82.6%) | 712 (77.9%) |
| Yes | 20 829 (7.1%) | 19 446 (6.8%) | 1181 (17.4%) | 202 (22.1%) |
| Previous CVA | ||||
| No | 273 241 (93.5%) | 266 444 (93.6%) | 6008 (88.3%) | 789 (86.3%) |
| Yes | 19 029 (6.5%) | 18 107 (6.4%) | 797 (11.7%) | 125 (13.7%) |
| Obesity | ||||
| No | 180 143 (61.6%) | 175 692 (61.7%) | 3947 (58.0%) | 504 (55.1%) |
| Yes | 112 127 (38.4%) | 108 859 (38.3%) | 2858 (42.0%) | 410 (44.9%) |
| Urolithiasis | ||||
| No | 284 996 (97.5%) | 277 490 (97.5%) | 6621 (97.3%) | 885 (96.8%) |
| Yes | 7274 (2.5%) | 7061 (2.5%) | 184 (2.7%) | 29 (3.2%) |
| Current or ex-smoker | ||||
| No | 87 442 (29.9%) | 85 350 (30.0%) | 1852 (27.2%) | 240 (26.3%) |
| Yes | 204 828 (70.1%) | 199 201 (70.0%) | 4953 (72.8%) | 674 (73.7%) |
| Alcohol excess | ||||
| No | 273 060 (93.4%) | 266 041 (93.5%) | 6210 (91.3%) | 809 (88.5%) |
| Yes | 19 210 (6.6%) | 18 510 (6.5%) | 595 (8.7%) | 105 (11.5%) |
| On diuretic | ||||
| No | 194 681 (66.6%) | 190 924 (67.1%) | 3346 (49.2%) | 411 (45.0%) |
| Yes | 97 589 (33.4%) | 93 627 (32.9%) | 3459 (50.8%) | 503 (55.0%) |
| Serum urate at diagnosis, micromol/L | 471 (100) | 470 (99) | 523 (117) | 558 (126) |
Baseline demographics and comorbidities in people with newly-diagnosed gout, separated into those who had hospitalizations for gout flares (single vs multiple) during the study period and those who had no hospitalizations. Data are presented as mean (s.d.) for continuous measures, and n (%) for categorical measures.
Baseline serum urate levels were available for 184 185 patients.
CKD: chronic kidney disease; CVA: cerebrovascular accident.