Table 3B.

XEN – Cox Proportional Hazard Model for risk of reoperation

	XEN
	Stand-alone XEN		XEN with Phacoemulsification
Multivariable Model	HR (95% CI)	P value	HR (95% CI)	P value
Age	0.99 (0.98 – 1.00)	P=0.094	0.99 (0.97 – 1.01)	P=0.476
Male a	0.88 (0.75 – 1.03)	P=0.113	1.00 (0.74 – 1.33)	P=0.974
Race/ethnicity b
- Non-Hispanic Black	1.52 (1.22 – 1.88)	P<0.001	1.56 (1.11 – 2.19)	P=0.012
- Hispanic/Latino	1.00 (0.73 – 1.36)	P=0.998	0.87 (0.50 – 1.49)	P=0.605
- Other e	1.59 (1.10 – 2.28)	P=0.013	0.97 (0.43 – 2.18)	P=0.936
Glaucoma diagnosis c
- Primary angle-closure glaucoma	1.08 (0.62 – 1.87)	P=0.790	1.14 (0.50 – 2.59)	P=0.752
- Normal Tension glaucoma	0.75 (0.39 – 1.47)	P=0.411	1.34 (0.56 – 3.21)	P=0.515
- Pigmentary/Pseudoexfoliation glaucoma	1.53 (1.16 – 2.02)	P=0.003	0.98 (0.54 – 1.81)	P=0.960
- Secondary glaucoma f	0.72 (0.48 – 1.09)	P=0.124	0.48 (0.19 – 1.18)	P=0.112
Glaucoma severity d
- Moderate	1.10 (0.75 – 1.60)	P=0.630	0.87 (0.38 – 2.00)	P=0.744
- Severe	1.32 (0.90 – 1.92)	P=0.159	1.76 (0.83 – 3.72)	P=0.152
Baseline IOP	1.03 (1.02 – 1.05)	P<0.001	1.08 (1.06 – 1.11)	P<0.001

Note:

Reference for Multivariate Model: age, gender ((a) reference: female), race ((b) reference: Non-Hispanic White), glaucoma type ((c) reference: Primary open angle glaucoma), severity ((d) reference: mild glaucoma)), and baseline IOP

^(e)Other race = non-Hispanic/Latino Asian, or other

^(f)Secondary glaucoma = glaucoma secondary to medications, trauma, inflammation, unspecified