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. 2023 Jul 3;20(1):398–408. doi: 10.1080/15476286.2023.2229596

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 6. — tRF expression profiles of CFS, EXO, MV, and EV-D. (A) Venn diagram to summarize unique and common tRFs across saliva fractions. (B) Relative expression levels of three most abundant tRFs in individual saliva fractions. (C-D) Box plot depicting the percentage distribution of tRFs across saliva fractions at individual donor level for glutamate (C), and glycine (D). (E-F) Composition of tRFs in individual saliva fractions for glutamate (E), and glycine (F). (G-H). Box plot depicting the percentage distribution of tRFs across saliva fractions at individual donor level for 5’-half tRFs (G) and 5’-tRFs (H). CFS, cell-free saliva; EXO, exosome; MV, microvesicle; EV-D, EV-depleted saliva; tRF, tRNA fragment.

*P < 0.05, **P < 0.01.