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. Author manuscript; available in PMC: 2023 Sep 1.

Published in final edited form as: Med Res Rev. 2022 May 23;42(5):1856–1887. doi: 10.1002/med.21893

Table 3.

Biomarkers used for diagnosis of IBD.

Biomarker		Concentration
Biomarker		UC	CD	Healthy or remission disease
Serological biomarker	CRP	20 mg/L	40 mg/L	1 mg/L – 3 mg/L
	ESR^*	~30 mm/h		~20 mm/h
	ASCA and p-ANCA
	NO	15.3 μM	14.5 μM	13.3 μM
	Cytokine (TNF-α, IL-102)	7.6 pg/ml (TNF-α) 144+34 pg/ml (IL-10)	12.7 pg/ml (TNF-α) 132+32 pg/ml (IL-10)	0.02 pg/ml (TNF-α) 44+9.5 pg/ml (IL-10)
	ST2	56.8 pg/ml		30.7 pg/ml
	TNFAIP6	5.8 ng/ml	5.6 ng/ml	2.4 ng/ml
	NGAL²¹³	87 ng/ml	90 ng/ml	60 ng/ml
Fecal biomarker	Calprotectin	1900 μg/g	3200 μg/g	34 μg/g
	S100A12	400 ng/ml	470 ng/ml	70 ng/ml
	Lactoferrin	1100 μg/g	440 μg/g	1 μg/g
	NGAL	6 μg/g	5 μg/g	0.3 μg/g
	MPO	100 μg/g	60 μg/g	4 μg/g
	MMP-9	6 ng/ml	2 ng/ml	0.6 ng/ml
	IAP	20% less	22% less	--
Urine biomarker	MMP-9²¹⁴	95%	91%	20%
	MMP-2²¹⁴	90%	89%	25%
	MMP9/NGAL²¹⁴	90%	86%	3%

^*

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