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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Med Res Rev. 2022 May 23;42(5):1856–1887. doi: 10.1002/med.21893

Table 4.

miRNA biomarkers present in blood and feces used for diagnosis of IBD.

Disease type Tissue Associated miRNAs Reference
CD Peripheral blood ↑: miR-1991-5p, miR362-3p, miR-340*, miR532-3p, miRplus-E1271
↓: miR-149*, miRplus-F1065		 215
UC Peripheral blood ↑: miR-28-5p, miR-151-5p, miR-199a-5p, miR-340*, miRplus-E1271, miR-103-2*, miR-362-3p, miR-532-3p, miR-3180-3p, miRplus-E1035, miRplus-F1159
↓: miR-505*		 215
CD Serum ↑:miR-140-3p, miR-877, miR-127-3p
↓:miR-150		 216
UC Serum ↑: miR-140-3p, miR-29a, miR-196b, miR-127-3p
↓: miR-150		 216
CD Serum ↑: miR‐146b‐5p 217
UC Serum ↑: miR‐146b‐5p 217
CD Serum
Feces		 ↑: miR-16, miR-21, and miR-223
↑: miR-223, miR-155		 218
UC Serum
Feces		 ↑: miR-16, miR-21, and miR-223
↑: miR-223, miR-155		 218
CD Feces ↑: miR-21, miR-106a, miR-96, miR-203, miR-20a, miR-326, and miR-92
↓: miR-320, miR-126, miR-484-5p, miR-143, miR-145, miR-16, and miR-125b		 219
UC Feces ↑: miR-21, miR-203, miR-126, and miR16
↓: miR-320 and miR-192		 219
CD Feces ↑: miR-223 and miR-1246 220
UC Feces ↑: miR-223 and miR-1246 220
CD Feces ↑: miR-135b, miR-223 and miR-451 221
UC Feces ↑: miR-221 and miR-18a 221

↑= increased expression, ↓= decreased expression