Table 1.
Correlation between SDPR/CPT1A and clinicopathological features
|
Characteristics |
SDPR expression | CPT1A expression | |||||
|---|---|---|---|---|---|---|---|
| n(%) | SDPR high | SDPR low | P-value | CPT1A high | CPT1A low | P-value | |
| Age (years) | |||||||
| ≥55 | 98(56.65) | 46 | 52 | 54 | 44 | ||
| <55 | 75(43.35) | 30 | 45 | 0.440 | 49 | 36 | 0.766 |
| Gender | |||||||
| Male | 92(53.18) | 42 | 50 | 53 | 39 | ||
| Female | 81(46.82) | 44 | 47 | 0.768 | 50 | 31 | 0.642 |
| TNM stage | |||||||
| I | 19(10.98) | 15 | 4 | 8 | 11 | ||
| II | 30(17.34) | 22 | 8 | 19 | 11 | ||
| III | 61(35.26) | 20 | 41 | 31 | 30 | ||
| IV | 63(36.42) | 19 | 44 | 0.000 | 45 | 18 | 0.042 |
| Tumor invasion | |||||||
| T1 | 11(6.36) | 9 | 2 | 4 | 7 | ||
| T2 | 21(12.14) | 15 | 6 | 10 | 11 | ||
| T3 | 63(36.42) | 25 | 38 | 34 | 29 | ||
| T4 | 78(45.08) | 27 | 51 | 0.001 | 55 | 23 | 0.029 |
| Lymph node metastasis | |||||||
| N0 | 48(27.75) | 29 | 19 | 15 | 33 | ||
| N1 | 38(21.97) | 19 | 19 | 21 | 17 | ||
| N2 | 43(24.85) | 17 | 26 | 29 | 14 | ||
| N3 | 44(25.43) | 11 | 33 | 0.006 | 38 | 6 | 0.000 |
| Distant metastais | |||||||
| M0 | 118(68.21) | 61 | 57 | 58 | 60 | ||
| M1 | 55(31.79) | 15 | 40 | 0.003 | 45 | 10 | 0.000 |
| Tumor differentiation | |||||||
| Well | 24(13.87) | 17 | 7 | 15 | 9 | ||
| Moderate | 59(34.10) | 34 | 25 | 30 | 29 | ||
| Poor | 90(52.03) | 25 | 65 | 0.000 | 58 | 32 | 0.242 |
| Helicobacter pylori | |||||||
| Negative | 49(28.32) | 35 | 14 | 25 | 24 | ||
| Positive | 124(71.68) | 41 | 83 | 0.000 | 78 | 46 | 0.151 |
| Overall survival | |||||||
| Survive | 73(42.20) | 48 | 25 | 37 | 36 | ||
| Die | 100(57.80) | 28 | 72 | 0.000 | 66 | 34 | 0.043 |