Figure 2.
Dectin-1 knockout restore cognitive functions of Aβ42 infusion model mice. (A) Representative average escape latency curves during place navigation test (four trials per day, during four consecutive days) and probe tests on day 5 without platform. N=40, N=10 mice per group. (B) Time course of escape latency, defined as the time taken to find the hidden platform. (C) Escape latency of all four groups on day 4. (D) The number of platform crossings. (E) The time in target quadrant. (F) Average swimming speed of mice in each group. (G) Total swimming distance of mice in each group. (H) Representative curves during novel object recognition test in each group. (I) Number of approaches in each group. (J) Total during of approaches in each group. (K) Total latency of all four groups.