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. 2023 Jun 21;14:1198171. doi: 10.3389/fgene.2023.1198171

FIGURE 4.

FIGURE 4

Schema of severity of Wolfram-Syndrome and Wolfram-related disorders. (A) Severity and clinical manifestations of Wolfram-related disorders and Wolfram Syndrome. (B) Severity of Wolfram Syndrome based on variant number and effect on coding sequence or transmembrane domain positions.