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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Ann Neurol. 2022 Nov 22;93(1):184–195. doi: 10.1002/ana.26542

Table 3.

Alzheimer Disease Neuropathologic Scores

AD Neuropathologic Change “ABC” Scores*
AD
Neuropathologic Change
Severity Scale
“A”
β-amyloid
“B”
Neurofibrillary
tangles
“C”
Neuritic
plaques
PDND (37)
0 13 4 36
1 14 28 1
2 7 5 0
3 3 0 0
 
PDD (114)
0 24 3 77
1 26 72 24
2 31 28 10
3 33 11 3
 
DLB (14)
0 2 1 9
1 5 8 2
2 3 4 3
3 4 1 0
*

Neuropathology scores according to Montine TJ, Phelps CH, Beach TG, et al. National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach. Acta Neuropathol 2012; 123:1–11