Table 5.
Lewy body stage | TDP-43 positivity No. of cases (total assessed) |
ARTAG No. of cases (total assessed) |
AGD No. of cases (total assessed) |
---|---|---|---|
PDND | |||
Braak 3 | 0 (4) | 0 (1) | 0 (5) |
Braak 4 | 0 (4) | 0 (3) | 0 (7) |
Braak 5 | 0 (13) | 1 (7) | 1 (15) |
Braak 6 | 1 (8) | 1 (4) | 2 (10) |
PDD | |||
Braak 3 | 0 (1) | 0 (1) | 0 (1) |
Braak 4 | 0 (6) | 3 (5) | 1 (6) |
Braak 5 | 2 (32) | 10 (19) | 1 (34) |
Braak 6 | 17 (58) | 7 (18) | 7 (73) |
DLB | |||
Braak 3 | 0 (1) | 0 (1) | 0 (1) |
Braak 4 | 0 (1) | 0 (1) | 0 (1) |
Braak 5 | 1 (4) | 0 (1) | 0 (6) |
Braak 6 | 1 (5) | 1 (2) | 0 (6) |
Lewy body stage according to Braak H, Del Tredici K, Rub U et al. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging 2003; 24:197–211
TDP-43: TAR DNA-binding protein immunoreactive neuronal cytoplasmic inclusions
ARTAG: age-related tau astrogliopathy
AGD: argyrophilic grain disease
PDND: Parkinson disease without dementia
PDD: Parkinson disease with dementia
DLB: dementia with Lewy bodies